Does the number of infused microspheres impact tumor dose in radioembolization? An analysis of resin versus glass Yttrium-90 microspheres
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چکیده
منابع مشابه
Radioembolization with yttrium-90 resin microspheres for neuroendocrine tumor liver metastases.
PURPOSE We aimed to evaluate the effectiveness and safety of radioembolization with yttrium-90 (90Y) microspheres in cases with unresectable neuroendocrine tumor liver metastases (NETLMs). METHODS Thirty patients (mean age, 55 years) underwent resin-based 90Y radioembolization for unresectable NETLM at a single institution between April 2008 and June 2013. Post-treatment tumor response was as...
متن کاملPost-radioembolization yttrium-90 PET/CT - part 2: dose-response and tumor predictive dosimetry for resin microspheres
BACKGROUND Coincidence imaging of low-abundance yttrium-90 (90Y) internal pair production by positron emission tomography with integrated computed tomography (PET/CT) achieves high-resolution imaging of post-radioembolization microsphere biodistribution. Part 2 analyzes tumor and non-target tissue dose-response by 90Y PET quantification and evaluates the accuracy of tumor 99mTc macroaggregated ...
متن کاملRadioembolization of liver tumors with yttrium-90 microspheres.
Radioembolization (RE), also termed selective internal radiation therapy (SIRT), has been gradually introduced to the clinical arsenal of cytoreductive modalities in recent years. There is growing evidence for efficiency in liver tumors of various entities, with the most prominent ones being hepatocellular carcinoma, colorectal cancer, and neuroendocrine tumors. Hepatic metastases of numerous o...
متن کاملInternal dosimetry for radioembolization therapy with Yttrium‐90 microspheres
The absorbed doses in the liver and adjacent viscera in Yttrium-90 radioembolization therapy for metastatic liver lesions are not well-documented. We sought for a clinically practical way to determine the dosimetry of this advent treatment. Six different female XCAT BMIs and seven different male XCAT BMIs were generated. Using Monte Carlo GATE code simulation, the total of 100MBq 90 Y was depos...
متن کاملThe development, commercialization, and clinical context of yttrium-90 radiolabeled resin and glass microspheres
Selective internal radiation therapy has emerged as a well-accepted therapeutic for primary and metastatic hepatic malignancies. This therapeutic modality requires the combined efforts of multiple medical disciplines to ensure the safe delivery of yttrium-90 (90Y)-labeled microspheres. The development of this therapy followed decades of clinical research involving tumor vascularity and microsph...
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ژورنال
عنوان ژورنال: Journal of Vascular and Interventional Radiology
سال: 2015
ISSN: 1051-0443
DOI: 10.1016/j.jvir.2014.12.300